What is ESRD?
ESRD, End Stage Renal Disease, occurs when chronic kidney disease developed into an advanced state which is after kidney failure. In this stage, your kidney function is less than 15% that can not meet body's needs. In this stage, toxins and extra fluids will build up in your body and cause symptoms.
What happened in ESRD?
As chronic kidney disease progresses to end-stage renal disease, signs and symptoms might include:
Nausea
Vomiting
Loss of appetite
Fatigue and weakness
Sleep problems
Changes in how much you urinate
Decreased mental sharpness
Muscle twitches and cramps
Swelling of feet and ankles
Persistent itching
Chest pain, if fluid builds up around the lining of the heart
Shortness of breath, if fluid builds up in the lungs
High blood pressure (hypertension) that's difficult to control
Signs and symptoms of kidney disease are often nonspecific, meaning they can also be caused by other illnesses. Because your kidneys are highly adaptable and able to compensate for lost function, signs and symptoms may not appear until irreversible damage has occurred.
What cause ESRD?
Diseases and conditions that can lead to kidney disease include:
Type 1 or type 2 diabetes
High blood pressure(Hypertension)
Glomerulonephritis, an inflammation of glomeruli
Interstitial nephritis, an inflammation of the kidney's tubules and surrounding structures
Polycystic kidney disease
Prolonged obstruction of the urinary tract, from conditions such as enlarged prostate, kidney stones and some cancers
Vesicoureteral reflux, a condition that causes urine to back up into your kidneys
Recurrent kidney infection, also called pyelonephritis