The progression speed of chronic kidney disease (CKD) has always been the concern of kidney patients.
Some kidney disease progresses rapidly, reaching uremia in a few years, while some nephropathy has not developed to renal failure in decades or even several decades. Although the ultimate outcome of CKD is ESRD, not all kidney diseases will go to uremia. This makes some kidney patients begin to care about the time of their condition to uremia.
How long does it take from kidney disease to kidney failure? How to judge and predict the speed of development of the disease?
This indicator may give you an answer: 24-hour urinary sodium and potassium
As the name implies, it is the detection of sodium and potassium ions in 24 hours urine. Sodium ion and potassium ion are irreplaceable minerals in human body. They play an important role in maintaining electrolyte balance and osmotic pressure in human body.
Why can these two indicators predict the development rate of kidney disease?
It was found that the higher the sodium intake, the faster the decline of glomerular filtration rate (GFR). The increase of 24-hour urinary sodium excretion is positively correlated with the decrease rate of glomerular filtration rate (GFR). When more potassium is ingested, it will penetrate into the excretion of sodium, thus reducing the effect of sodium on GFR, decreasing the burden of kidney metabolism, and helping to stabilize blood pressure so as to play a role in delaying renal function.
Another study was to observe renal function by analyzing the ratio of 24-hour urinary sodium to urinary potassium. Facts show that the higher the ratio, the greater the risk of renal function deterioration, and the faster the progress. These studies mainly focus on patients before stage 4 of kidney disease, but there is no study on uremic or dialysis patients.
Many kidney patients may have a good understanding of 24-hour urinary protein quantification, but little attention has been paid to 24-hour urinary sodium and 24-hour urinary potassium. This study also demonstrates the rationality of the low-salt diet we usually recommend for kidney patients.
Now since you know the indicators that affect the progression speed up of kidney disease. You should pay attention to them. For more information on kidney disease treatment, please leave a message below or contact online doctor.
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- Tag: CKD CKD Prognosis
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