For some Purpura Nephritis patients, they are also often detected with IgA Nephropathy. Do you know the relation between IgA and purpura? In this article, you will find out the answer.
Among all immune complexes, IgG is the most common antibody, for example, post-streptococcal glomerulonephritis is caused by this IgG immune complex. But the antibody in the immune complex of Henoch-Schonlein Purpura is IgA.
After various infections, the IgA content in the blood will increase, and the increased IgA will be degraded by the liver. However, some children produce significantly higher IgA after infection than the general children, or some children have poor ability to degrade IgA in the liver. As a result, the level of IgA in the blood is too high, which creates a basis for the formation of immune complexes with IgA as antibody.
For children with Henoch-Schonlein purpura, Immunopathological examination of the kidney, skin and intestine shows that the rate of IgA deposition in glomeruli, mesentery and skin is higher than that in other organs and tissues.
In pediatric clinic, there is also a common disease called IgA Nephropathy, which also has a large number of IgA deposits in the kidney, but no clinical manifestations of skin and gastrointestinal tract. Sometimes people call IgA nephropathy allergic purpura without skin rash.
How to eliminate IgA deposition from the kidneys for purpura nephritis patients?
You can try systemic Chinese medicine treatment, such as Toxin-Removing Treatment. This treatment makes use of Micro-Chinese Medicine Osmotherapy, Medicated Bath, Foot Bath, Enema Therapy and so on to eliminate excessive substances such as IgA immune complexes from the blood. It can also dissolve IgA deposition in the kidneys and restore the balance of anti-inflammatory cytokines and pro-inflammatory cytokines to reduce renal inflammation and control the disease from getting worse. Moreover, it can help regulate the abnormal immune system and reduce its excess production of IgA.
After about one week’s treatment, you will see floccules in urine, which are those IgA immune complexes being passed out. After about one month’s treatment, Purpura Nephritis will be under control, and its associated symptoms, such as skin rash, hematuria, proteinuria, swelling and so on will get relieved greatly.
Now you know the relation between IgA and Purpura. For more information on its treatment, please leave a message below or contact online doctor.
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- Tag: Purpura Nephritis Causes Purpura Nephritis
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