In the progression of kidney disease, various complications will appear, among which proteinuria and serum creatinine are the two of the more prominent symptoms. Both of them can reflect renal function.
Proteinuria is not only a mirror reflecting renal function, but also an independent risk factor affecting renal function. Although serum creatinine can reflect kidney function, it is not sensitivity. If both of them are high for long term, it is not a good thing to maintain renla function. And they are both the products of reduced renal function.
However, some renal patients meet such a problem: proteinuria is reduced, while creatinine level is still high. Then is kidney function bad or good?
Proteinuria reduces and creatinine level is still high: this is a good thing.
Proteinuria is caused by the decrease of filtration function and the increase of filtration pore after impaired renal function. The more protein leaks, the more serious the impairment of filtration function, which will aggravate renal fibrosis. When proteinuria is controlled, protein leakage decreases, kidney tissues and cells can be repaired. At this time, renal function stops deteriorating and begins to improve, forming a virtuous cycle, and then proteinuria will also be reduced.
Creatinine is the product of muscle metabolism, and the garbage in the body, because the impaired kidney function can not be metabolized in time, resulting in creatinine accumulation. Creatinine at a higher level is a response to impaired renal function, which can not be reversed, so it is difficult to decrease creatinine, but it can not be said that high creatinine means poor renal function and serious illness.
Overall, proteinuria is a more important indicator than serum creatinine. It is a key indicator affecting the development of renal function and the prognosis of nephropathy. Serum creatinine has less influence. Therefore, do not worry too much if proteinuria is reduced, while creatinine level is still high. Maintaining the stability of renal function is the key.
To stabilize proteinuria and serum creatinine level, two things should be done.
1. Diagnosis is the key to targeted treatment.
There are many factors causing the increase of proteinuria and serum creatinine. Besides the impairment of renal function, some other effects can not be ignored. First of all, clear diagnosis and targeted treatment are the fastest and most effective way. There are many factors affecting these two indicators, including medication, diet, infection and other factors. Drug abuse can lead to the time limit of treatment, and even aggravate the deterioration of renal function, which will inevitably affect the indicators; a low amount of high-quality protein diet is more conducive to reducing proteinuria and serum creatinine, which some renal patients do not do well; in addition, infection, fever and other factors will accelerate the immune inflammation reaction in the kidney, leading to the rise of creatinine. As long as the causes are eliminated, you can control the disease well.
2. Regular reexaminations to prevent relapse
Frequent recurrence of kidney disease is a major problem in the treatment of nephropathy. Every relapse means that kidney function is damaged once. To reduce the risk of recurrence, regular reexaminations are crucial.
Proteinuria regular review is mainly to check the urine routine. Kidney patients should pay attention to urine protein +, -, 24 hours of urine protein quantitative, urine microalbumin, proteinuria creatinine ratio and other indicators;
Blood creatinine is to check blood routine, at the same time to observe uric acid, urea nitrogen, cystatin c, hemoglobin, potassium, phosphorus and other indicators of electrolyte reaction. These are also the key indicators of renal function.
Now what it means with reduced proteinuria and high creatinine level. If you still have any other questions on kidney disease, please leave a message below or contact online doctor.
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