Antihypertensive medicine is to help lower blood pressure, but sometimes even though your blood pressure is not high, your doctor still prescribe it. Do you know why? It is to help you prevent uremia.
Mr. Liu, in his 50s, is a Diabetic Nephropathy patient with high blood pressure. Because of poor blood sugar control, blood pressure increases. In the last two years of physical examination, lab report showed that his urine protein was 3+, which means that the disease has developed to 3rd-4th stages of kidney disease, and entered the refractory stage. Mr. Liu was very upset. Because of the disease, he often lost his temper, as a result, his blood pressure could not be controlled well, so he went to the hospital for further treatment. Blood pressure was controlled after regular use of antihypertensive drugs, and urinary protein was reduced to +.
After being discharged from hospital, the doctor lets Mr. Liu continue to take blood pressure medicine, he was very puzzled: why antihypertensives are needed even though blood pressure is normal? Won’t it cause low blood pressure?
Why do nephrologists often prescribe antihypertensive drugs to patients without high blood pressure?
The doctor emphasizes that as long as Diabetic Nephropathy patients take the medicine under the guidance of doctors, low blood pressure won’t occur. Those medicines do not only control blood pressure, but also reduce proteinuria so as to help you fight against the disease effectively.
1. Give full play to the effect of antihypertensive drugs and reduce blood pressure
80% of kidney patients will have elevated blood pressure, and hypertension will lead to the rapid development of kidney disease to uremia, so you should strictly control the blood pressure within a reasonable range.
2. Antihypertensive drugs not only reduce blood pressure, but also reduce urinary protein
There are many antihypertensive drugs in the department of nephrology, but only two antihypertensive drugs can play a role in reducing proteinuria and protecting kidney function. They are ACEI and ARBs. They are to take effect by reducing the pressure on the kidneys and decreasing the protein that the glomerulus filters through. Urinary protein is a risk factor for deterioration of kidney function. The presence of persistent urinary protein may lead to renal failure and lead to uremia.
3. ACEI and ARBs can protect renal function.
The two drugs not only lower blood pressure and urinary protein, but also help protect kidney function in patients with kidney disease. It can slow down glomerular sclerosis, delay the deterioration of kidney function, slow down renal failure to a certain extent, and avoid the occurrence of uremia.
Notice when using ACEI and ARBs
-When kidney patients without high blood pressure take antihypertensive drugs, it is necessary to take blood pressure at any time. Because although the doctor may use the dosage of medicine within the range of acceptable blood pressure, in order to achieve a good effect of reducing urinary protein, the dosage will be very high.
-ACEI and ARBs belong to renin-angiotensin receptor blocker, which has certain effect of increasing serum potassium. Regular review is required when taking drugs to avoid hyperkalemia.
-After taking ACEI or ARBs, creatinine level will be affected. When serum creatinine elevation > 30% or even higher than 50% (>130 umol/L), you should stop the medicine.
Now do you know why you have to use antihypertensive drugs even though your blood pressure is not high? For more information on CKD associated problems, such as proteinuria, creatinine, hematuria and swelling, please leave a message below or contact online doctor.
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