Recent data show that glomerulonephritis is the leading cause of uremia (also known as ESRD), followed by diabetes mellitus and hypertension. Then there are polycystic kidney disease (PKD), as well as kidney diseases caused by lupus erythematosus, drug-induced kidney damage, hepatitis B, gout and so on.
Going back to the roots, there are many causes of uremia, including genetic problems, congenital development, infection, systemic diseases, diabetes, urinary tract obstruction, hypertension, poisoning, renal insufficiency, compression, poor lifestyle and air pollution (PM2.5), etc.
No.1 Glomerulonephritis
The causes are complex and varied, including congenital and acquired, primary and other diseases involving the kidney.
Among them, infection is the most common cause. The pathogenesis of a variety of Nephrotic Syndrome and IgA Nephritis have infection, such as cold, gastroenteritis, urinary tract infection and so on. Many people call nephritis "cold sequelae". Infection →immune inflammation→ proteinuria / hematuria, this is a common pathogenesis. Therefore, prevention of infection is also an important part of kidney disease treatment.
No.2 Diabetes
Diabetes is the leading cause of uremia in the developed countries. Usually after suffering from diabetes for 5 years, Diabetic Nephropathy associated symptoms will appear. At present, diabetic nephropathy has become the most common type of kidney disease in China. Renal failure in diabetic patients usually occurs 10 years later.
No.3 High blood pressure
The kidney is a mass of capillaries that are very sensitive to changes in blood. In the early stage of Hypertensive Nephropathy when kidney failure does not occur, there are generally no symptoms and fewer proteinuria, which many people will not detect. When renal failure occurs, there are obvious symptoms.
Some of the causes can not be changed, such as genetic problems such as hereditary nephritis, Fabry disease, and some membranous nephropathy caused by air pollution, etc. These account for a small part and are not discussed much.
Most of the causes of uremia can be avoided by your own behaviors. Patients with confirmed kidney disease should avoid these factors, which not only prevent the aggravation of kidney disease, but also help improve the condition of the disease. For more information on uremia treatment, please leave a message below or contact online doctor.
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- Tag: ESRD ESRD Causes
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