Since getting kidney disease, patients usually have two problems in mind:
1. Can my disease develop into uremia or ESRD? How quickly is it?
2. Do I have to take medicine for lifetime? When can I stop the medication?
We've talked enough about the first question, which is that uremia does not come so quickly; In terms of medication, my opinion is that if you want to stop drugs or reduce drugs as soon as possible, your currently drugs have to achieve the optimal curative effect. Only in this way can chronic kidney disease (CKD) be controlled timely, and discontinuation of drugs will become a reality.
As a kidney patient, you must know steroids, anti-hypertensive drugs, immunosuppressants, Chinese patent medicine, etc. When taking them, you need to know the following skills.
1. Steroids
The optimal time for steroid drugs (e.g., prednisone, prednisone, methylprednisolone, etc.) is 7 a.m. to 8 a.m.
The reason lies in that the peak value of human secretion of glucocorticoid occurs at 8 to 10 am, so when we take the drug at 7 to 8 am with the regulation of human body's own glucocorticoid secretion, it will help to reduce the risk of hypofunction and cortical atrophy of the upper gland cortical.
2. Immunosuppressants should be taken with empty stomach.
Immunosuppressive agents (such as cellcept, cyclosporine, tacrolimus, etc.), which are greatly affected by the intake of food, should be taken within 1 hour before meals or 2 hours after meals, and the two immunosuppressive agents of cyclosporine and tacrolimus should not be taken together with grapefruit so as to avoid unstable blood drug concentration.
3. ACEI and ARBs
ACEI and ARBs have been highly recommended in the department of nephrology, and they play a prominent role in stabilizing blood pressure and protecting renal function.
However, to ensure the effect of those medications, patients should limit salt diet, which should not exceed 5g per day. The high-salt diet will reduce the clinical efficacy of such drugs in lowering blood pressure and lowering proteinuria.
4. Simvastatin should be taken at night.
Cholesterol synthesis occurs mainly in the evening, but the commonly used lipid-lowering drug, simvastatin, has a short half-life, and its efficacy in the body is correspondingly short, so it is best to take lipid-lowering drugs in the evening when synthetic cholesterol peaks.
And long half-life lipid-lowering drugs such as atorvastatin and rosuvastatin can be taken at any times a day without limiting the night.
5. Ferrous succinate can not be taken together with tea.
In clinical practice, ferrous succinate is a commonly used drug to deal with anemia. However, when taking tea, the tannins in tea and iron agents will produce hard-to-absorb precipitates. The human body's ability to absorb iron will be significantly affected, and blood toning will be twice as effective.
Now you know the best time to take medicine. Hope the above tips can help you. For more information on ESRD treatment, please leave a message below or contact online doctor.
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- Tag: ESRD ESRD Treatment
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