Is it possible to have a safe pregnancy with Lupus Nephritis? If you would like to become a mother, this article will be very helpful for you.
For Lupus Nephritis patients, pregnancy may make the disease flare up and trigger the relapse of disease, and meanwhile lupus itself can increase the risk of pregnancy. But over the past few decades, the incidence of adverse pregnancy outcomes in Lupus patients has dropped significantly as a result of the development of treatment regimens and immunosuppressants. Therefore, most women of reproductive age in SLE have access to pregnancy opportunities and can safely get through pregnancy with the joint and close monitoring of obstetricians, nephrologists and patients.
Pregnancy risk of Lupus Nephritis (LN)
Many antibodies in SLE patients are associated with adverse outcomes of pregnancy, such as gestational hypertension, premature birth, abortion, internal growth retardation, etc. In addition, changes in hormone levels, autoantibodies and internal environment during pregnancy are also closely related to the activity, recurrence and even worsening of lupus nephritis.
How to choose the right time for pregnancy?
It is important to choose the right time of pregnancy to reduce adverse outcomes. It is generally believed that LN patients must simultaneously satisfy the following conditions before pregnancy can be considered:
-No vital organs are involved;
-Stable condition at least 6 months, preferably more than 1 year;
-The dosage of prednisone is less than 10mg/d (preferably 10mg/d on alternate days).
-Normal serum creatinine;
-24-hour urinary protein is less than 0.5g.
-Stop the use of immunosuppressive agents such as mycophenolate, cyclophosphamide, MTX, and tripterygium for at least half a year;
-Gonadal function is normal.
Lupus can damage blood vessels throughout the body, including the placenta and uterus. If lupus is active during pregnancy, it can cause stillbirth and premature removal of the placenta. The latter cause massive hemorrhage and kill pregnant women. Therefore, patients with lupus nephritis during pregnancy should visit the doctors every two weeks during pregnancy, and during the entire pregnancy and postpartum for two months, you need to be under the close supervision of doctors to prevent lupus from flaring up.
Is it possible to have a safe pregnancy with Lupus Nephritis? Yes, it is possible, but the precondition is that you should bring Lupus Nephritis under control firstly. For more information on lupus nephritis treatment, please leave a message below or contact online doctor.
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