For most kidney patients, they are troubled by proteinuria. How to reduce it or even make it negative? Here we list 12 methods to lower proteinuria. Hope they can help you.
1. Antihypertensive drugs
It includes ACEI and ARBs. These drugs have obvious advantages: wide indications, and definite effect of reducing urinary protein. Routine dosage can reduce urinary protein by 15-20%, and kidney patients usually need to use 2-4 times the dose to improve the effect of reducing proteinuria, which often can reduce more than half of the urinary protein. Besides, they have the effect of lowering blood pressure and protecting renal function.
2. Glucocorticoids
It includes:
Short-acting steroids (its effect is usually not obvious.)
Intermediate-acting steroids (Effects and side effects are balanced and used most often.)
Long-acting steroids (The side effects are relatively large.)
It has powerful functions of anti-inflammation, anti-allergy, anti-shock and immunosuppression. And its effect of reducing urinary protein is obvious, and it is widely used in most primary nephropathy and some secondary nephropathy.
However, because of the side effects of steroids, only when 24 hour urine protein is over 1g or even 4g, they can be used.
3. Immunosuppressants
Immunosuppressive drugs have a strong immunosuppressive effect. Inhibiting immunity can alleviate the immune inflammation of kidney and reduce urinary protein. Moreover, they are often used in conjunction with steroids when steroids do not take effect.
4. Rituximab
Rituximab is also an immunosuppressant, but its efficacy is even more prominent. Especially when urinary protein is ineffective, it can help achieve a good effect. It is a targeted drug with less side effects, but its high price limits its wide application.
5. Spironolactone
Spironolactone is commonly used drug in kidney disease to pass extra fluid out of the body. In addition, spironolactone, as an aldosterone antagonist, can reduce the intraglomerular pressure, thereby reducing urinary protein and protecting renal function.
6. Statins
Statins are commonly used in Nephrotic Syndrome patients with hyperlipidemia, which can reduce urinary protein and blood lipid. For patients with low blood lipid, statins can also play a role in reducing urinary protein.
7. Traditional Chinese Medicine
It can not only reduce urinary protein, but also reduce the side effects of Western medicine and improve the immune function of patients. If you would like to get a better effect, systemic Chinese medicine treatment will be a good choice, for example, Toxin-Removing Treatment.
8. Low amount of high-quality protein diet
To take 50-100g lean meats a day (including eggs and soy products). Reduce the intake of vegetable protein as much as possible, which can help to reduce urinary protein.
9. Low salt diet
Reducing daily salt intake to less than 6g can reduce urinary protein by about 15% and blood pressure by 5-10mmHg.
10. SGLT2 inhibitors
SGLT2 (sodium-glucose synergistic transporter 2) inhibitors, such as Canagliflozin, are suitable for patients with Diabetic Nephropathy. At the same time, it can reduce urinary protein and slow down the progress of renal failure.
11. To lose weight
Obesity can cause proteinuria. Weight loss can sometimes play a better role than drugs in reducing urinary protein;
12. Treatment of infection
Infection often occurs in kidney patients. Inflammation of respiratory tract, intestine, urinary tract and oral cavity is very common, especially gingival diseases. Most people have a little more or less of them. After these inflammations are cured, urinary protein is often significantly reduced.
Now you know the 12 methods to reduce proteinuria. If you do not know which method is suitable for you, you can leave a message below or send emails to tsthospital@hotmail.com. Our renal experts will help you.
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